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Showing posts with the label drug delivery

Cell penetrating peptide - playing around with the metabolic different between cancer and normal cells

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  LONZA is the company selling the Amaxza’s reagents. Generating peptides ( which turn into alpha-helix when exposed to acidic microenvironments like cancers. The team used peptide as a drug carrier to specifically target the cancer cell, especially the solid tumors. Roughly estimate the MW - > 4000 g/mol -- it seems like their peptides incorporate into the membrane but don't interfere with cell permeability otherwise it could cause inflammation (due to the internal content leakage) Ref: https://www.cybrexa.com/wp-content/uploads/2018/12/Cybrexa-Poster-63.pdf Patent: https://patents.google.com/patent/US20190209580A1/en?oq=US+20190209580+A1 Company profile: https://www.cybrexa.com/about/

Survey around on drug discovery and delivery process - Thai University and Research Center

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Just google it and save for the record; Biotech (drug discovery); http://www.biotec.or.th/en/index.php/global-networks/biotec-novartis-drug-discovery-partnership Mahidol University (drug discovery); http://ecdd.sc.mahidol.ac.th/ http://sisyspharm.org/index.php/en/ Thammasat University (drug discovery); http://www.sat.tu.ac.th/tuddd/tuddd_main.php Chulalongkorn University (drug discovery); https://www.research.chula.ac.th/chula4dr-eng/ Prince Songkla University (drug delivery); http://dds.pharmacy.psu.ac.th/index.php Pharmaceutical Research and Manufacturers Association http://www.prema.or.th/www/index.php?lan=th Few slides that I got from google searching Source:  https://apac-asia.com/images/achievements/pdf/6th/03-03.pdf Where else that I miss?